Bear in mind this medication has been prescribed for the reason that your health care provider has judged that the reward to you personally is greater than the potential risk of Negative effects. Many individuals applying this medication don't have serious Unintended effects.
Get this medication by mouth with or without having meals as directed by your medical professional, normally every single four to six hours as wanted. This medication is usually taken with foods if stomach upset takes place. Drink an abundance of fluids after you use this medication Until usually directed by your medical professional.
Confined knowledge recommend that utilization of promethazine hydrochloride throughout labor and shipping does not have an considerable effect on the period of labor or delivery and isn't going to enhance the risk of have to have for intervention inside the newborn.
Abuse and dependancy are separate and distinctive from Bodily dependence and tolerance. Health and fitness treatment suppliers needs to be mindful that dependancy is probably not accompanied by concurrent tolerance and indicators of Actual physical dependence in all addicts. On top of that, abuse of opioids can occur in the absence of correct dependancy.
Because recurrences of NMS have been noted with phenothiazines, the reintroduction of promethazine HCl should be carefully thought of.
Nevertheless it helps many people, this medication contains a hazard for abuse and will from time to time induce habit. This danger may very well be bigger if you have a substance use problem (like overuse of or habit to drugs/Liquor).
Never just take this medication for many days ahead of allergy tests mainly because check results is usually afflicted.
Promethazine need to be employed cautiously in persons with cardiovascular disease or with impairment Promethazine codeine syrup of liver functionality.
The mixture of promethazine hydrochloride and codeine phosphate must be utilised with caution in pediatric sufferers six yrs and more mature (see Warnings-Use in Pediatric Patients).
Do not arise or sit up swiftly, particularly if you are an more mature affected person. This reduces the potential risk of dizzy or fainting spells. Alcohol may possibly interfere with the result of this medication. Stay away from alcoholic beverages.
g., amiodarone, quinidine) might end in a rise in codeine plasma concentrations and a minimize in Energetic metabolite morphine plasma concentration which could lead to an analgesic efficacy reduction or indications of opioid withdrawal.
Respiratory depression leading to arrest, coma, and Demise has occurred with the use of codeine antitussives in youthful little ones, specifically from the beneath-one-12 months infants whose power to deactivate the drug will not be entirely developed.
Opioid analgesics and antitussives, including codeine, among the active ingredients in Promethazine HCl and Codeine Phosphate Oral Answer, shouldn't be Employed in sufferers with acute febrile illness related to effective cough or in individuals with Serious respiratory disease in which interference with power to very clear the tracheobronchial tree of secretions would've a deleterious impact on the individual’s respiratory perform.
The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric people under 6 a long time of age, mainly because The mixture may well bring about fatal respiratory despair With this age inhabitants. It is important that promethazine with codeine syrup is measured having an exact measuring machine (see Safeguards-Information and facts For People).